| |
PEEP 5
|
PEEP 12
|
p-value
|
|---|
|
HR, bpm
|
97 ± 16
|
92 ± 14
|
0.02
|
|
SAP, mmHg
|
109 ± 13
|
122 ± 17
|
0.12
|
|
DAP, mmHg
|
77 ± 16
|
81 ± 12
|
0.58
|
|
MAP, mmHg
|
89 ± 15
|
93 ± 13
|
0.65
|
|
Double product
|
10593 ± 411
|
11214 ± 459
|
0.17
|
|
Central venous pressure, mmHg
|
7 ± 2
|
8 ± 3
|
0.96
|
|
SpO2, %
|
94 ± 3
|
96 ± 3
|
0.89
|
|
VT, mL
|
597 ± 121
|
613 ± 130
|
0.33
|
|
RR, ripm
|
14 ± 1
|
14 ± 2
|
0.99
|
|
Catecholamine
|
12 (17%)
|
15 (21%)
|
0.21
|
|
Blood sample
|
|
Hb, g/dL
|
12 ± 1
|
12 ± 2
|
0.92
|
|
pH
|
7.37 ± 0.07
|
7.35 ± 0.06
|
0.05
|
|
PaO2, mmHg
|
70.2 ± 6.2
|
112.8 ± 2.1
|
<0.0001
|
|
PaCO2, mmHg
|
38.6 ± 8.8
|
38.7 ± 7.8
|
0.96
|
|
HCO3
−
|
22.1 ± 2.3
|
21.8 ± 1.6
|
0.03
|
|
BE
|
−2.4 ± 0.8
|
−3.5 ± 0.6
|
0.04
|
|
SaO2, %
|
93 ± 3
|
97 ± 2
|
0.02
|
|
PaO2/FiO2 ratio
|
179 ± 24
|
271 ± 38
|
<0.0001
|
|
ScvO2, %
|
63 ± 5
|
57 ± 3
|
0.01
|
|
Lactate, mmol/L
|
3.2 ± 1.1
|
6.7 ± 1.5
|
0.001
|
- Abbreviations: HR heart rate, bpm beats per minute, SAP systolic arterial pressure, DAP diastolic arterial pressure, MAP mean arterial pressure, SpO
2 hemoglobin saturation by pulse oximetry, V
T
tidal volume, RR respiratory rate, ripm respiratory incursion per minute, Hb hemoglobin, pH hydrogen potential, PaO
2 arterial oxygen pressure, PaCO
2 arterial carbon dioxide pressure, HCO
3
− bicarbonate, BE base excess, SaO
2 arterial oxygen saturation, ScvO
2 oxygen saturation of central venous blood. Values are expressed in mean ± standard deviation or frequency
