Table 2 Baseline characteristics

Gender^a (F:M)

N = 4:1

N = 5:0

N = 4:1

Age (years)^b

52.0 (41.0, 69.0)

54.0 (34.0, 72.0)

37.0 (27.0, 74)

EDSS^b

4.5 (2.0–4.5)

2.5 (2.5–4.5)

2.5 (1.5–4.5)

No/unilateral/bilateral aid

N = 5/0/0

N = 5/0/0

N = 4/0/1

T25FW^c (seconds)

5.6 (5.2, 6.2)

7.0 (5.3, 7.0)

4.9 (4.6, 5.4)

6MWT^c (metres)

367.5 (348.0, 435.2)

380.6 (337.2, 392.0)

460.5 (442.9, 476.8)

MFIS physical sub^c

21.0 (2.0, 25.0)

12.0 (10.5, 25.0)

16.0 (9.0, 21.0)

MFIS cognitive sub^c

17.0 (11.5, 22.5)

3.0 (0.0, 16.5)

11.0 (11.0, 14.0)

MFIS psychosoc sub^c

2.0 (1.0, 4.0)

2.0 (0.0, 5.0)

3.0 (1.5, 5.0)

MFIS total score^c

40.0 (17.5, 51.0)

28.0 (13.0, 39.0)

30.0 (23.5, 38.0)

MFIS total score ≥ 38

N = 3/2

N = 2/3

N = 1/4

MSIS-29 physical sub^c

45.0 (17.5, 49.4)

20.0 (17.5, 39.4)

16.2 (10.6, 35.6)

MSIS-29 psychological sub^c

27.8 (18.0, 33.3)

11.1 (17.5, 39.4)

11.1 (8.3, 25.0)

KVIQ-G-10 visual sub^c

21.0 (17.5, 23.5)

20.0 (17.5, 24.5)

21.0 (17.5, 24.0)

Median visual score^c

4.2 (3.5, 4.7)

4.0 (3.5, 4.9)

4.2 (3.5, 4.8)

KVIQ-G-10 kinaesthetic sub^c

15.0 (13.5, 18.5)

24.0 (15.5, 24.5)

23.0 (18.0, 23.5)

Median kinaesthetic score^c

3.0 (2.7, 3.7)

4.8 (3.1, 4.9)

4.6 (3.6, 4.7)

KVIQ-G-10 total^c

40.0 (31.0, 40.0)

43.0 (33.5, 49.0)

44.0 (36.0, 47.0)

Median total score^c

4.0 (3.1, 4.0)

4.3 (3.3, 4.9)

4.4 (3.6, 4.7)

TDMI 25 s right^c

15.0 (12.0, 22.0)

14.0 (12.0, 16.0)

16.0 (11.5, 23.0)

TDMI 15 s left^c

10.0 (9.0, 11.5)

9.0 (7.5, 11.0)

13.0 (6.5, 14.5)

TDMI 45 s right^c

27.0 (19.5, 36.0)

23.0 (19.0, 31.0)

33.0 (20.0, 38.5)

TDMI 15 s left2^c

10.0 (8.5, 12.0)

8.0 (8.0, 9.5)

12.0 (7.5, 13.0)

TDMI 25 s left^c

16.0 (14.5, 19.5)

16.0 (14.5, 18.0)

20.0 (12.0, 21.0)

TDMI Spearman’s r^c

0.72 (0.47, 0.82)

0.59 (0.46, 0.72)

0.87 (0.80, 0.97)