Table 3 Walking, fatigue and quality of life post-intervention data for each study group

Change from baseline^a

−0.1 (−0.7, −0.1)

−0.4 (−0.9, −0.3)

−0.4 (− 0.4, − 0.3)

Post-intervention^a

5.1 (5.0, 5.5)

6.0 (4.9, 6.0)

5.0 (4.2, 5.1)

Participants with clinically significant improvement (≥20%)

N = 1/5

N = 0/5

N = 0/5

Change from baseline^a

85.5 (59.4, 97.1)

65.1 (39.5, 74.8)

33.6 (11.6, 77.7)

Post-intervention^a

453.2 (450.5, 470.0)

418.0 (412.0, 469.0)

476.5 (465.0, 569.3)

Participants with clinically significant improvement (≥20%)

N = 3/5

N = 2/5

N = 2/5

Change from baseline^a

−3.0 (−7.5, 4.0)

−2.0 (−13.5, −0.5)

−3.0 (−6.5, −1.5)

Post intervention^a

14.0 (9.0, 19.5)

9.0 (1.0, 21.5)

12.0 (7.5, 15.0)

Change from baseline^a

−4.0 (−5.5, 0.5)

−3 (−9.5, 0.0)

−2.0 (−4.5, −0.5)

Post intervention^a

15.0 (10.0, 18.0)

0.0 (0.0, 7.0)

10.0 (6.5, 13.0)

Change from baseline^a

0.0 (−1.0, 0.0)

0.0 (−3.5, 0.0)

−2.0 (−2.5, −0.5)

Post intervention^a

2.0 (0.5, 3.5)

0.0 (0.0, 2.5)

1.0 (0.0, 3.5)

Change from baseline^a

−9.0 (−13.0, 4.5)

−6.0 (−23.5, −3.0)

−9.0 (− 10.5, −4.5)

Post intervention^a

26.0 (22.0, 41.0)

12.0 (2.5, 28.0)

23.0 (15.0, 30.5)

MFIS total score ≥ 38 (post-intervention)

N = 2/5

N = 0/5

N = 0/5

Change from baseline^a

−1.2 (− 11.9, 3.7)

−7.5 (− 13.7, − 2.5)

− 2.5 (−8.1, 6.2)

Post intervention^a

27.5 (18.7, 48.1)

16.2 (8.1, 30.6)

21.2 (10.6, 30.0)

Change from baseline^a

0.0 (−11.1, 9.7)

−5.5 (−6.9, 2.8)

−5.5 (−9.7, 1.4)

Post intervention^a

30.6 (11.1, 37.5)

5.6 (0.0, 23.6)

8.3 (4.2, 19.4)