From: Questioning the “SPIN and SNOUT” rule in clinical testing
PPV | probability increase (%) for P(1∖+) | |||||||||
prevalence | prevalence | |||||||||
SE | SP | LR+ | 0.2 | 0.4 | 0.6 | 0.8 | 0.2 | 0.4 | 0.6 | 0.8 |
0.8 | 0.8 | 4.00 | 0.50 | 0.73 | 0.86 | 0.94 | 0.30 | 0.33 | 0.26 | 0.14 |
0.4 | 0.8 | 2.00 | 0.33 | 0.57 | 0.75 | 0.89 | 0.13 | 0.17 | 0.15 | 0.09 |
0.8 | 0.4 | 1.33 | 0.25 | 0.47 | 0.67 | 0.84 | 0.05 | 0.07 | 0.07 | 0.04 |
0.4 | 0.4 | 0.67 | 0.14 | 0.31 | 0.50 | 0.73 | −0.36 | −0.42 | −0.36 | −0.21 |
NPV | probability increase (%) for P(0∖-) | |||||||||
prevalence = P [1] | 1-prevalence = P(0) | |||||||||
SE | SP | LR- | 0.2 | 0.4 | 0.6 | 0.8 | 0.8 | 0.6 | 0.4 | 0.2 |
0.8 | 0.8 | 0.25 | 0.94 | 0.86 | 0.73 | 0.50 | 0.14 | 0.26 | 0.33 | 0.30 |
0.4 | 0.8 | 0.75 | 0.84 | 0.67 | 0.47 | 0.25 | 0.04 | 0.07 | 0.07 | 0.05 |
0.8 | 0.4 | 0.50 | 0.89 | 0.75 | 0.57 | 0.33 | 0.09 | 0.15 | 0.17 | 0.13 |
0.4 | 0.4 | 1.50 | 0.73 | 0.50 | 0.31 | 0.14 | −0.07 | −0.10 | −0.09 | −0.06 |